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The activation of NMDA leads to depolarizing of the neuronal cells and increases the influx of calcium and sodium ions into the cell (Shen et al., 2006)

doi:10.1534/genetics.111.128033 Murata, K., & Kimura, A

It should be noted that hyperuricemia in both men and women is a significant contributor to the development of non-alcoholic fatty liver disease (NAFLD), diabetes, the metabolic syndrome, and obesity

In most animal experiments, AS model mice exhibit a significant reduction in GM diversity, an increase in the relative abundance of Turicibacter , Desulfovibrio , Lactococcus , Enterococcus , and an decrease in the relative abundance of Bacteroides , Roseburia , Lactobacillus , and Alloprevotella [51,52,53,54,55,56]