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In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia

Contraindications Vitamin B1, Vitamin B6 and Vitamin B12 is contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation

Common Side Effects Gastrointestinal effects: Nausea, diarrhea, vomiting, and constipation top the list of adverse events

A comprehensive search was conducted across PubMed, Embase, Web of Science and Cochrane Library databases, without timeframe limits, resulting in a total of 1085 scientific articles