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lediglich zu Beginn gibt es einen kleinen "Pieks" von der Nadel

Structural-functional analyses reveal that the conserved catalytic glutamate residue (human E115/murine E116) is essential for enzymatic activity, as its substitution with glutamine completely abrogates glutathione degradation capacity [11]

In contrast, MitoSOX levels were elevated only in the group with LC symptoms when compared to NC (Figure 3D), while no differences were found in intracellular levels of lipid peroxidation and glutathione amongst the groups (Figure 3E and 3F, respectively)

Overall, the MD data was consistent with the markedly different dynamics observed in the cryo-EM 3DVA with the ECDs undergoing substantially greater dynamic motions in the Cagri-AMY 3 R complex than observed in the parallel rAmy-AMY 3 R complex (Supplementary Fig