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The molecular docking study showed that 55 and 56 made a hydrogen bond with the Arg880 residue via the tetrazole ring, as well as another hydrogen bond with Ser876

Ahmed Hamdi OA, Syed Abdul Rahman SN, Awang K, Abdul Wahab N, Looi CY, Thomas NF, et al

Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis

In the absence of mutations in DNA repair-coding genes, FA can also underly a variant of a human inherited bone marrow failure syndrome (IBMFS) caused by mutations in both ALDH2 and ADH5 10, 14
