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2018;13(7):e0200477
10.1038/s41598-020-74735-0 168 YaoT.AsayamaY
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In a co-cultured system containing 3T3-L1 adipocytes and RAW 264 macrophages, Dioscin administration was shown to suppress inflammation via down-regulating the expressions of tumor necrosis factor (TNF), nitric oxide (NO), and monocyte chemoattractant protein-1 (MCP-1), as well as the phosphorylation of c-Jun N-terminal kinase (JNK) in macrophages (Hirai et al., 2010)
