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Such changes are associated with resistance mechanisms targeting the respiratory chain (oxidative phosphorylation)
Because of impaired endothelial barrier function, there is an imbalance in released vasodilatory substances (such as NO, angiotensin II, thromboxane A2), further exacerbating vascular constriction
Meanwhile, these images were adjusted to 512*512 for segmentation and quantitation by model A
The homogenate extract from both Zebrafish larvae and the CAM layer of chick embryo was centrifuged at 12,000 g for 15 min at 4 C to remove cellular debris
