Blood Alcohol Concentration
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Description
Activation of TLR3 receptors in microglia causes increased release of IL-1 and TNF-, which increases SERT expression in astrocytes and, therefore, 5-HT reuptake and its degradation to the metabolite 5-HIAA, thus reducing extracellular 5-HT levels
8(2): R44-R54
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In addition, factors including ageing, poor diet, smoking, excessive alcohol consumption, chronic disease, and certain medications may disrupt normal methylation patterns
