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The active center is located in a shallow cavity at the interface between the two subunits of the dimer

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Prostaglandins Other Lipid Mediat 91:130138 Minami K, Ueda N, Maeda H, Ishimoto K, Otagaki S, Tsujiuchi T (2019) Modulation of chemoresistance by lysophosphatidic acid (LPA) signaling through LPA 5 in melanoma cells treated with anticancer drugs