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Whole-brain mapping of amylin-induced neuronal activity in receptor activity-modifying protein 1/3 knockout mice

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Extracellular iron is taken up by cells and transported to the mitochondria, where it is utilized for the synthesis of cofactors including heme and iron-sulfur (Fe/S) clusters essential to the function of enzymes involved in oxidation-reduction reactions, DNA synthesis and repair, and a variety of other cellular processes [76]

The overexpression of CYP1A1 usually caused due to exposure to PAHs results in the increase in ROS generation (Figure 1)