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If youre exploring peptides because: GLP-1 side effects are limiting, youve plateaued and want a smarter plan, or youre trying to lose fat without sacrificing muscle, then the right next step is a structured metabolic review: whats driving weight, whats driving hunger, whats driving adherence, and which interventions actually address your bottleneck

Studies indicate that in the absence of appropriate medical intervention, approximately 20% of patients with diabetic wounds will require lower limb amputation, with a subsequent one-year mortality rate of 13% post-diagnosis 19,20

Allen LH, Hampel D, Shahab-Ferdows S, et al

If tolerated, the documented approach is to stay at the current step for the full interval before the next scheduled escalation not to leapfrog steps