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Plus any folate that is ingested in the diet is sooner or later also stuck in the folate trap
Evidence for these combinations remains limited to case reports and small case series, but interest is growing

Many heavy drinkers miss out on having a balanced diet rich in vitamin B12

Presently, isatuximab is approved for the treatment of RRMM in combined therapy with pomalidomide and dexamethasone [79] and, in patients who have undergone two prior therapies, in combination with carfilzomib and dexamethasone [80]