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FOXO4-DRI is a synthetic senolytic peptide developed to selectively target and eliminate senescent cells, often referred to as "zombie cells." These dysfunctional cells accumulate with aging and are associated with chronic inflammation, tissue degeneration, and age-related decline

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Researchers induced knee osteoarthritis in rabbits using collagenase injections, then treated the animals with weekly intra-articular injections of AOD-9604, hyaluronic acid, or a combination of both compounds
