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found that active GSH metabolism within tumors further suppresses immune responses, such as IFN- signaling and PD-1/PD-L1 interactions, while reducing the number of M1 macrophages and increasing the proportion of M2 macrophages

Aging in females was characterized by a significant rise in IL-1, IL-4, IL-5, IL-6, IL-10, IL-12(p40), IL-12(p70), IL-17, CXCL-10, CXCL-1, MIP-1, MIP-2, and TNF, but several of these cytokines and chemokines were restored to a more youthful level with mAb treatment (Fig

A modern classification of OHSS

To support this, we compiled representative PK data for toxic TCMs listed in the Chinese Pharmacopoeia (ChP), as summarized in Table S1, Additional File 1