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Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

If left unchecked, superoxide radicals break DNA strands, and since DNA repair is one of glutathiones many functions, more glutathione has to be used for repairs

Itoh et al

In yet another loop, clockwork orange ( cwo ), a transcriptional repressor, competes with CLK-CYC to bind on E-boxes, and suppresses the expression of CLK-CYC target genes, including its own
