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Swanson JA, Antonoff MB , Maddaus MA, DCunha J
Collectively, these data support the conclusion that increased cellular GSSG accumulation in hepatocytes plays a critical role in the pathogenesis of NAFLD and may represent a potential therapeutic target for the treatment of NAFLD
This was investigated further, and, when faced with a low-glucose/low-glutamine environment, these cells were shown to rely on fatty acid oxidation or acetate for energy to mount a cytokine response, further highlighting the metabolic resilience of NK cells
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