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A roughly 20% increase in the endogenous GSH level was observed after a 3-h treatment with GSH exogenously, which could reduce the frequency of all types of chromosomal aberrations and aberrant metaphases induced by 1 and 2 Gy of X-rays and also decreased the tail in the comet assay, an indicative of radiation protection

Akt is a central early effector in the phosphatidylinositol 3-kinase-protein kinase B (PI3K) pathway, where it mediates the cellular insulin response and promotes proliferation

Excess labile iron is stored by ferritin, whereas NCOA4 facilitates ferritin-bound iron into the cytosol via ferritinophagy-mediated degradation of ferritin (Fig