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Intraneuronal aggregates of -syn that are intracellularly localized and bound to cellular membranes are capable of triggering ferroptosis through these aggregate-membrane interactions ( 3.2 Relationship between PD-related genes/proteins and ferroptosis PD pathophysiology is significantly influenced by genetic predisposition, with numerous gene loci linked to its development (133)

Brain Pathol (2008) 18:1308

The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis

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