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Fahey, Director of Research & Operations, COREsea, personal communication, 2025)
287 The currently developed JHU-083 is a prodrug of 6-Diazo-5-oxo-L-norLeu (L-DON) generation glutaminase inhibitor that selectively activates L-DON in the TME
But its not without its shortcomings L-AA can be irritating, especially for sensitive skin, its only water soluble, and it has a very short shelf life
Nov 1 2008;233(9):1425-31
