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doi: 10.1093/brain/awu377 [DOI] [PMC free article] [PubMed] [Google Scholar] 58
It goes directly to the source of the injury, whether that is a swollen gum, a twisted ankle, or an inflamed joint, and reduces the chemical reaction causing the pain
In addition to regulating osteoclast differentiation and activity, estrogen directly controls osteoclast survival by promoting osteoclast apoptosis
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