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Certain chemo drugs are metabolized using the UGT1A1 enzyme

Vitamin C, Lung Function and Airway Hyperresponsiveness As asthmatics have both lower vitamin C levels and intake, the supplementation of this vitamin may ameliorate the course of asthma by lowering the number of asthma attacks (exacerbations), the asthma symptom score, the ICS need [280], and decreasing respiratory symptoms such as sore throat or cough in exercise- and cold-induced asthma after stimulation [37,39]

However, because IGF-1 signaling is involved in cellular proliferation pathways implicated in oncogenesis, existing or precancerous conditions are considered absolute contraindications

[DOI] [PubMed] [Google Scholar] Cooper A.J.L., Pinto J.T., Krasnikov B.F., Niatsetskaya Z.V., Han Q., Li J., Vauzour D., Spencer J.P.E