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Importantly, the IGF-1R is also critical for the increased expression of StAR under FSH stimulation, which is required for mitochondrial transport of cholesterol for the first step of sex steroid synthesis, pregnenolone production (60)

References Bayen S, Carpentier C, Baran J, Cottencin O, Defebvre L, Moreau C, Devos D, Messaadi N

doi: 10.1016/j.freeradbiomed.2005.08.009

It dissolves readily in ethanol, methanol, acetonitrile, and ethyl acetate but has poor solubility in hydrocarbon solvents [35]