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These free radicals are generated from molecules of oxygen, nitrogen, and sulfur, which, because of their unpaired electrons, react vigorously with other molecules to generate ROS and RNS

It is astonishing that notwithstanding the Tietzes method for glutathione titration is the most cited one in the literature (4111 hits on Scopus database) and most of the commercially available kits are still based on its procedure, his findings and warnings on GSSG values have been rapidly and are still consistently ignored

IV or injectable therapy is administered in clinic and bypasses digestion, which some patients prefer

10.1016/j.pcad.2005.01.004 89 HsiehH