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The reason is that LPS causes an immune response

*The plasma which leaks from damaged blood vessels contains pro-inflammatory mediators including, but not limited to, vascular endothelial growth factor (VEGF), prostaglandin E2 (PGE2), and pro-inflammatory cytokines

[DOI] [PubMed] [Google Scholar] 40.Ibrahim M.A., Geddawy A., Abdel-Wahab S

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