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However, in general, all studies have shown that exposure to IR leads to a decrease in the diversity and richness of the biological community, an increase in the abundance of pathogenic bacteria (Proteobacteria and Fusobacteria), and a reduction in beneficial bacteria ( Faecalibacterium and Bifidobacterium ) (92, 97)

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First evidence was provided by the anaerobic oxidation of thiol group of human serum albumin (HSA) with NO which resulted in the formation of sulfenic acid and nitrous oxide (N 2 O) [112]

doi: 10.1093/jn/132.6.1299