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4 Mechanism of the protective effect of PCs on diabetes mellitus 4.1 Improve the insulin resistance Insulin, an essential hormone secreted by pancreatic -cells, regulates glucose metabolism and exerts a profound influence on blood glucose levels ( Located in the cell membrane, the insulin receptor exhibits a tetrameric structure with two -chains and two -chains, serving as the primary hub for insulin action and orchestrating the insulin signaling cascade

To sum up, magnesium supplementation illustrates clear potential in alleviating PCOS symptoms by modulating glucose and lipid metabolism, improving insulin signaling transduction, and exerting synergistic anti-inflammatory and antioxidant effects

5 Oxidative stress, inflammation, and cell death Increased ROS and oxidative stress damage mitochondrial DNA, disrupt cellular metabolism, and exacerbate insulin dysregulation (78, 79)

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