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Certain dog breeds, notably the Giant Schnauzer, Border Collie, and Beagle, carry a genetic predisposition for cobalamin malabsorption

in contrast, the cytotoxicity of the PtII drugs, cisplatin and carboplatin, was only significantly increased in one of the two relatively resistant lines (SKOV-3) and in the sensitive (CH1) line after GSH depletion

twice daily) was well tolerated but did not significantly shorten gastrointestinal recovery time compared with placebo, leading to discontinuation of its development for this indication

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