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Description
The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis

39 By FcBP-functionalization, the mucus-permeability of PEG-NP was not impaired

CPI is simple to calculate, CPI = 91 - (0.65 percent predicted DLCO) - (0.53 percent predicted FVC) + (0.34 percent predicted FEV 1 ) , and has been shown to reflect the extent of disease more accurately than single physiologic indices [38]

Correlation analysis was performed using R software (version 4.1.2, The R Foundation for Statistical Computing, Gut microbiome analyses Fecal samples were collected from WT mice ( n = 5) and Nrf2-KO mice ( n = 10) from the same litter, all of which had not been exposed to noise
