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Topical GHK-Cu is generally considered safe for cosmetic use, but injectable forms are largely unregulated research chemicals

They are administered in controlled doses by healthcare professionals

A A W van Geloven, E R Hendriks, B ter Horst, M M N Leeuwenburgh, O van Ruler, J M Vogten, E J C Vriens, M Westerterp (Department of Surgery, Tergooi Hospital, Hilversum)