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However, particular attention should be given to the possibility of worsening melasma due to epidermal heating, especially in non-insulated RF therapy

10.1016/j.stem.2014.09.017 70 GrimmigB.DalyL.HudsonC.NashK.BickfordP

Fernando Ayala-Zavala, Centro de Investigacin en Alimentacin y Desarrollo, Mexico Updates Copyright 2015 Carmona-Ribeiro, Prieto and Nantes

Through this receptor it also shares insulin-like metabolic activity , including increased glucose uptake, which is the basis for its hypoglycemia risk
