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APs were not designed based on a deep understanding of the changes in neurocircuitry in schizophrenia, but were discovered fortuitously and there is still a general lack of understanding of the specific mechanisms underlying both their therapeutic efficacy and their potent metabolic side effects 49

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Su papel clsico es facilitar la oxidacin de grasa , pero se ha propuesto que pueda atenuar la degradacin proteica y favorecer la sntesis de msculo, sobre todo en personas mayores o con dficit de carnitina