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Our study also found that HG-treated HK-2 cells showed increased LPO and MDA levels, impaired mitochondrial morphology, imbalanced redox homeostasis, and reduced ATP production, whereas dapagliflozin treatment improved hyperglycemia-induced mitochondrial dysfunction
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Conversely, MAO-B15 showcased the formation of new hydrogen bonds with Cys-172, Tyr-326, and Tyr-435
