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In conclusion, while polyphenolic compounds hold considerable promise for neurodegenerative disease therapy, future research should prioritize refining their delivery mechanisms, expanding clinical evidence, and exploring their role in combination therapies to maximize their therapeutic benefits
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Spechenkova et al., 2021)
A genome-wide association study demonstrated that the serine/threonine kinase encoding - ATM gene (ataxia telangiectasia mutated) has potential involvement in the mechanism of enzymes responsible for response to metformin (Zhou et al., 2011)
