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Cancers 9 (11), 145
The K447R evident mutation significantly reduced the lactylation of USP2 under TGF1 stimulation compared to USP2 WT, USP2 K139R, USP2 K205R, USP2 K241R, K340R, K420R, K464R, and K473R (Fig
Conclusions IGF-1 has numerous beneficial and protective effects on the CV system, including anti-apoptotic and pro-survival effects on cardiomyocytes and vascular bed cells, tissue remodeling effects, cardiac development and contractility stimulation, vasodilation and decreased vasoconstriction
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