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Description
Increased levels of Ca v channel mRNA within dorsal root ganglion neurons have been demonstrated in paclitaxel-treated mice, and Ca v channel antagonists (gabapentin and ethosuximide) effectively reduce hyperalgesia in rodents with paclitaxel- and vincristine-induced CIPN [17]

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A minimal block of tissue was excised and immersed briefly in H20, then transferred to a watch glass containing 2% aqueous uranyl acetate (Ted Pella) for 2 hrs at room temperature

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