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Cells, sequentially for 2 weeks in patterning 42 and 2 weeks in IL22 + maturation 42 media (both scTS2/16 + ), had retained the capacity to differentiate toward enterocytes, goblet cells, Paneth cells and enteroendocrine cells (Fig

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Statins inhibit the rate-limiting step of cholesterol biosynthesis, blocking the reduction of HMG-CoA reductase to mevalonate
