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You take it only when needed, 45 to 60 minutes before

This stimulates the production of excessive testosterone by thecal cells, disrupting the hypothalamic-pituitary-ovarian (HPO) axis, ultimately affecting dominant follicle generation, follicular dysfunction, and ovarian interstitial cell fibrosis ( 2.1.2 Uterus Successful pregnancy, encompassing embryo adhesion, implantation, growth, invasion of trophocytes, and formation and functional maintenance of the placenta, requires precise regulation of immune cells and inflammatory factors at the maternal-fetal interface to establish immune tolerance (53)

doi: 10.1073/pnas.89.10.4412

Unless you have truly complex medical issues, Marek is massive overkill