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[3] Glucose Pyruvate Alanine Pyruvate Glucose Although originally described in skeletal muscle, the glucose-alanine cycle is not restricted to muscleliver interactions, but also involves other extrahepatic tissues, including cells of the immune system

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The significantly longer aripiprazole apparent half-life compared to oral aripiprazole (mean 75 hours) is attributed to the dissolution and formation rate-limited elimination of aripiprazole following ARISTADA administration

It is contraindicated in certain conditions such as active malignancy and must be used cautiously in those with diabetes, prediabetes, or a history of pituitary disease, which is why careful screening and regular monitoring are essential