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Fluid retention, which may lead to or exacerbate heart failure, can occur with concomitant use of thiazolidinediones (TZDs) with insulin
Ann Microbiol (2020) 70:1

While ionophores demonstrate preclinical efficacy, clinical outcomes remain inconsistent, highlighting challenges such as narrow therapeutic windows, metabolic heterogeneity, and compensatory resistance mechanisms

doi: 10.1016/j.jad.2014.07.009
