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In another in vivo study, coadministration of venlafaxine 150 mg/day, with a single 1-mg dose of risperidone, slightly inhibited its conversion of risperidone to 9-hydroxyrisperidone (9-OH-risperidone), which is partially metabolized by CYP-2D6

Deborah Langheld ND, MPH "Chris Masterjohn takes a comprehensive approach including 1) scholarly and critical approach by digging through the published literature, 2) functional approach by analyzing the biochemical pathways 3) understanding variability among individuals by showing what genetic polymorphisms change individual requirements

Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, et al

Mast cells in the skin degranulate in response to the injected medication, releasing histamine that activates nerve endings and creates that maddening itch