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Description
Preclinical studies showed no adverse effects across several organ systems including liver, spleen, lung, kidney, brain, thymus, prostate, and ovaries in studies up to 6 weeks

Development of a new reporter gene systemdsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier

[DOI] [PubMed] [Google Scholar] 160.Holmgren A

After achieving optimal results, many patients transition to a maintenance protocol with less frequent dosing