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Notably, Withaferin A treatment also increased the levels of mono-oxygenated (+1) PE and PC species, which may be products of lipids peroxidized via the lipid peroxidase activity of GPX4 16
This was further corroborated by studies using a short interfering-RNA against CaMKK-, which abolished -lipoic acid-induced AMPK activation

(2012) Cardiac hypertrophy in deceased users of anabolic androgenic steroids: an investigation of autopsy findings
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