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vitamin b12 deficiency injections not working Working? Your Cofactors Might Be the Problem : r/B12_Deficiency Vitamin B12 Deficiency in Aging:
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In POTS, this signaling fails, leading to blood pooling in the lower extremities and a rapid, compensatory spike in heart rate

However, a 2024 systematic review in the Journal of Clinical Endocrinology and Metabolism concluded that evidence for inositols benefits remains limited and inconclusive for broader populations beyond PCOS

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Strict vegans and vegetarians may develop deficiency over time, as B12 is found almost exclusively in animal products
