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Individuals known to have alcohol addiction will be excluded, as will individuals with a history of epilepsy or who have implanted metallic devices such as pacemakers (for whom neurophysiological testing is contraindicated)

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5-amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide using S-adenosylmethionine (SAM)