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However, the inclusion of a denaturant, such as SDS, may be necessary to ensure rapid labeling of all free cysteine residues because about 20% of total cellular protein thiols are not susceptible to modification by NEM under native conditions [24]
The recently developed MSU Crystal Deposition Quantification (MSKF) scoring system, which quantifies urate burden based on ultrasound features (e.g., double-contour sign and tophi), has been validated for distinguishing asymptomatic hyperuricemia from gout
When I asked about the decision, she crossed her arms and furrowed her brow
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