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However, when accounting for within-patient clustering using a MANCOVA with patient as a fixed effect, the multivariate omnibus test was significant, and univariate effects remained significant for insomnia and end-of-dose crash, but not for poor appetite or return of symptoms

Moreover, the zeta potentials of pFeSAN in water and acetate buffer (pH 4.0) were 24.3 and 14.2 mV, respectively, indicating the stable dispersion of pFeSAN under various environments (Supplementary Fig