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Another study on cardiometabolic risk factors in a diabetes case-control study (NCT02588898) and a vitamin-supplementation trial (NCT02586181) found high plasma concentrations of metabolites, including TMAO and choline, correlated with lower cholesterol and plasma phospholipid levels, suggesting TMAO may aid in cholesterol solubilization and macrophage cholesterol (158)

Andrologia 49(10):e12762 Aitken R, Smith T, Lord T, Kuczera L, Koppers A, Naumovski N, Connaughton H, Baker M, De Iuliis G (2013) On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid

Valproic Acid and the Liver Injury in Patients with Epilepsy: An Update

doi: 10.1186/s12978-021-01257-x [DOI] [PMC free article] [PubMed] [Google Scholar] 199