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One nsSNP was located in the FAD/NAD-binding domain, which serves as the FAD/NAD-binding domain involved in oxidative metabolism of a variety of hydrocarbons (rubredoxin reductase, putidaredoxin reductase, terpredoxin reductase, ferredoxin-NAD + reductase components of benzene 1,2-dioxygenase, toluene 1,2-dioxygenase, chlorobenzene dioxygenase, biphenyl dioxygenase), NADH oxidase and NADH peroxidase1, 2, 3

Your doctor may decide not to use IV metronidazole if you have uncontrollable high blood pressure (resistant hypertension), congestive heart failure, or significant fluid retention