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BioFactors (Oxford, England), 35 (6), 500508

Stomach upset Diarrhea Nausea Vomiting Fatigue Eye irritation Skin rash Less common: Low blood pressure, anaphylactic shock, asthma attacks, headache Case reports Light sensitivity: Occurred in pulmonary fibrosis patients taking NAC in combination with pirfenidone

However, recent reports have found that autophagy may also play an important role in the induction of ototoxicity by aminoglycosides, and autophagy may be protective mechanism of hearing (He et al., 2020

User 3 split his 500mcg dose as 250mcg every 12 hours specifically to account for what he cited as a 4 to 6-hour half-life