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Furthermore, the discovery of new advantageous mutations remains an active area of research
In comparison, functional dystonia (FD) may resemble other forms of dystonia (OD) but has a different pathophysiology, as a subtype of functional movement disorders (FMD)
The ERK pathway exerts anti-apoptotic effects by inhibiting Bim and upregulating Bcl-2 expression, whereas the JNK/p38 pathway initiates apoptosis by activating Bim, Bad, and Bax
While these functional improvements occurred in animal models, they suggest possible benefits for mobility and quality of life that would need confirmation in human trials
