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Mov Disord Clin Pract 6:96103
Dysbiosis can affect the kynurenine pathway of tryptophan metabolism, leading to an imbalance in neuroactive metabolites that influence mood, cognition, and pain perception (Seton et al., 2023)

doi:10.1002/phar.1396

Further research in the nanoscale phenomena governing biological materials and the heterojunction between cells and substrate could allow osteoinductive implants coupled with osteoconductive properties